Computel: Computation of Mean Telomere Length from Whole-Genome Next-Generation Sequencing Data
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چکیده
منابع مشابه
Computel: Computation of Mean Telomere Length from Whole-Genome Next-Generation Sequencing Data
Telomeres are the ends of eukaryotic chromosomes, consisting of consecutive short repeats that protect chromosome ends from degradation. Telomeres shorten with each cell division, leading to replicative cell senescence. Deregulation of telomere length homeostasis is associated with the development of various age-related diseases and cancers. A number of experimental techniques exist for telomer...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0125201